PE-22-28 (10 mg Vial)
PE-22-28 is a shortened analogue of spadin, the propeptide fragment released during sortilin maturation. It blocks the TREK-1 potassium channel, a mechanism distinct from the monoamine pathways most antidepressant research has centred on.
- Purity
- Exceeds 99% (HPLC/MS)
- Form
- Lyophilized powder
- Presentation
- 10 mg vial
- Availability
- In stock
Sold for research, laboratory, or analytical purposes only. Not for human consumption.
About PE-22-28 (10 mg Vial)
TREK-1 blockade is the whole point of the molecule, so assays that do not measure channel activity or its downstream consequences will not distinguish it from an inert control. This listing is the 10 mg vial.
Like everything in the Bioregulators range, this vial is lyophilized, sealed, and accompanied by third-party purity documentation for its batch.
Research applications
PE-22-28 (10 mg Vial) appears in the following research contexts. These are descriptions of published laboratory work, not instructions for use:
- TREK-1 potassium channel assays
- Antidepressant mechanism research
- Sortilin propeptide studies
Product specification
- Product name
- PE-22-28 (10 mg Vial)
- SKU
- CP-PE-22-28-10-MG
- Category
- Bioregulators
- Presentation
- 10 mg lyophilized powder
- Purity
- Exceeds 99%, verified by HPLC/MS
- Testing
- Independent US laboratory, per batch
- Availability
- In stock
CAS number, molecular formula and sequence are published per batch on the certificate of analysis.
Handling, reconstitution and storage
Store the sealed vial of lyophilized PE-22-28 at -20°C, protected from light. Allow it to reach room temperature before opening so that moisture does not condense onto the powder.
Reconstitute with bacteriostatic water directed down the inside wall of the vial rather than onto the cake, and swirl instead of shaking — mechanical agitation is the most common cause of degradation in peptide handling. Keep reconstituted solution at 2-8°C and validate its working life for your own assay conditions.
Frequently asked questions
- How is PE-22-28 (10 mg Vial) supplied and stored?
- It ships as a lyophilized powder in a sealed vial. Store the lyophilized product at -20°C protected from light; once reconstituted with bacteriostatic water, keep it refrigerated at 2-8°C and use it within the window your protocol validates.
- Is a certificate of analysis available?
- Yes. Every batch is independently tested by a US laboratory and verified to exceed 99% purity by HPLC/MS. Request the COA for your batch number and we will send the report.
- How long does delivery take?
- Orders dispatch within two business days and ship within the United States. Delivery cost is confirmed with your quote.
- Can PE-22-28 (10 mg Vial) be used in humans or animals?
- No. This product is sold strictly for research, laboratory and analytical purposes. Human and animal consumption is prohibited.
